# Biotech Catalyst Monitor - Clinical Trial Readouts & Signals (`datasignalslab/biotech-catalyst-monitor`) Actor

Track upcoming clinical trial readouts, phase transitions and results from ClinicalTrials.gov, scored by stock-moving impact. A self-serve catalyst signal for biotech investors and traders.

- **URL**: https://apify.com/datasignalslab/biotech-catalyst-monitor.md
- **Developed by:** [DataSignals Lab](https://apify.com/datasignalslab) (community)
- **Categories:** AI, Agents, Developer tools
- **Stats:** 2 total users, 1 monthly users, 100.0% runs succeeded, NaN bookmarks
- **User rating**: No ratings yet

## Pricing

from $200.00 / 1,000 company analyzeds

This Actor is paid per event and usage. You are charged both the fixed price for specific events and for Apify platform usage.

Learn more: https://docs.apify.com/platform/actors/running/actors-in-store#pay-per-event

## What's an Apify Actor?

Actors are a software tools running on the Apify platform, for all kinds of web data extraction and automation use cases.
In Batch mode, an Actor accepts a well-defined JSON input, performs an action which can take anything from a few seconds to a few hours,
and optionally produces a well-defined JSON output, datasets with results, or files in key-value store.
In Standby mode, an Actor provides a web server which can be used as a website, API, or an MCP server.
Actors are written with capital "A".

## How to integrate an Actor?

If asked about integration, you help developers integrate Actors into their projects.
You adapt to their stack and deliver integrations that are safe, well-documented, and production-ready.
The best way to integrate Actors is as follows.

In JavaScript/TypeScript projects, use official [JavaScript/TypeScript client](https://docs.apify.com/api/client/js.md):

```bash
npm install apify-client
```

In Python projects, use official [Python client library](https://docs.apify.com/api/client/python.md):

```bash
pip install apify-client
```

In shell scripts, use [Apify CLI](https://docs.apify.com/cli/docs.md):

````bash
# MacOS / Linux
curl -fsSL https://apify.com/install-cli.sh | bash
# Windows
irm https://apify.com/install-cli.ps1 | iex
```bash

In AI frameworks, you might use the [Apify MCP server](https://docs.apify.com/platform/integrations/mcp.md).

If your project is in a different language, use the [REST API](https://docs.apify.com/api/v2.md).

For usage examples, see the [API](#api) section below.

For more details, see Apify documentation as [Markdown index](https://docs.apify.com/llms.txt) and [Markdown full-text](https://docs.apify.com/llms-full.txt).


# README

## Biotech Catalyst Monitor - Clinical Trial Readouts & Signals

**See the trial events that often move biotech stocks, before they happen.** Give one or more company names and get their clinical trials from ClinicalTrials.gov, ranked by potential market impact: upcoming Phase 3 readouts, results just posted, and phase transitions. Not a raw trial dump - a curated catalyst dataset.

> A single Phase 2 or Phase 3 readout can move a biotech stock 20-80% in a day. This Actor surfaces those catalysts per company, scored and ranked.

**Real example (from live data):** *Moderna - top catalyst: a Phase 3 trial, active, with primary completion 2026-06-30, scored impact 100 (an upcoming readout).* Highest-impact events are ranked first.

### What makes it different
Most clinical-trial scrapers return raw study records. This one computes the signal:

- **Catalyst classification** - upcoming readout, results posted, completed-awaiting-results, or status change.
- **Impact score (0-100)** - later phases and near-term readouts rank highest (Phase 3 readout > Phase 1 status note).
- **Per-company ranking** - the trials most likely to move the stock, first.
- **Verifiable** - every catalyst includes a direct link to the study on ClinicalTrials.gov.

### Who it's for
- **Biotech investors and traders** - a ready-made trial-catalyst dataset for research and monitoring.
- **Fintech and research apps** - drop trial catalysts into your product.
- **Pharma competitive-intelligence teams** - track a competitor's pipeline and readout timing.

Pairs with our SEC insider, 13F and 8-K actors for a full market-catalyst suite.

### Input
| Field | Type | Description |
|---|---|---|
| `sponsors` | array | Company / sponsor names (e.g. Moderna, Vertex Pharmaceuticals, BioNTech). |
| `maxStudies` | integer | Trials to scan and rank per company. |
| `minImpact` | integer | Only return catalysts at or above this impact score (e.g. 70 = high-impact only). |

### Output
One item per company: the company query, trials found, a high_impact_count, and a ranked list of catalysts. Each catalyst has the NCT id, title, phase, status, primary completion date, the catalyst type, an impact score, and a direct study URL.

### How it works
Reads trials from the official **ClinicalTrials.gov v2 API** (free, public, no key, JSON). It matches the sponsor field, falls back to full-text when needed, then classifies and scores each trial. Clean, stable, fast - no scraping fragility.

### Pricing
**Pay-per-event: per company analyzed.** Scan a 10-company watchlist = 10 charges. You pay only for what you scan.

### FAQ
**Which companies can I track?** Any sponsor in ClinicalTrials.gov. Use the company name; the Actor matches the sponsor field and falls back to full-text.
**How current is it?** ClinicalTrials.gov is the official U.S. registry, updated continuously; each run reads the latest data.

---
*Keywords: clinical trials, biotech catalyst, trial readout, PDUFA, phase 3 results, ClinicalTrials.gov API, biotech investing, catalyst calendar, drug pipeline, pharma intelligence, biotech catalyst data.*

---
**Note:** Provided as data for research, screening and monitoring - not investment advice. Historical patterns do not guarantee future results.

# Actor input Schema

## `sponsors` (type: `array`):

One or more biotech/pharma company names (trial sponsors), e.g. Moderna, Vertex Pharmaceuticals, BioNTech. Each is scanned for stock-moving trial catalysts.
## `maxStudies` (type: `integer`):

How many of the company's trials to scan and rank.
## `minImpact` (type: `integer`):

Only return catalysts at or above this impact score (e.g. 70 = high-impact: Phase 3 readouts, results). 0 = all.

## Actor input object example

```json
{
  "sponsors": [
    "Moderna",
    "Vertex Pharmaceuticals"
  ],
  "maxStudies": 50,
  "minImpact": 0
}
````

# API

You can run this Actor programmatically using our API. Below are code examples in JavaScript, Python, and CLI, as well as the OpenAPI specification and MCP server setup.

## JavaScript example

```javascript
import { ApifyClient } from 'apify-client';

// Initialize the ApifyClient with your Apify API token
// Replace the '<YOUR_API_TOKEN>' with your token
const client = new ApifyClient({
    token: '<YOUR_API_TOKEN>',
});

// Prepare Actor input
const input = {
    "sponsors": [
        "Moderna",
        "Vertex Pharmaceuticals"
    ]
};

// Run the Actor and wait for it to finish
const run = await client.actor("datasignalslab/biotech-catalyst-monitor").call(input);

// Fetch and print Actor results from the run's dataset (if any)
console.log('Results from dataset');
console.log(`💾 Check your data here: https://console.apify.com/storage/datasets/${run.defaultDatasetId}`);
const { items } = await client.dataset(run.defaultDatasetId).listItems();
items.forEach((item) => {
    console.dir(item);
});

// 📚 Want to learn more 📖? Go to → https://docs.apify.com/api/client/js/docs

```

## Python example

```python
from apify_client import ApifyClient

# Initialize the ApifyClient with your Apify API token
# Replace '<YOUR_API_TOKEN>' with your token.
client = ApifyClient("<YOUR_API_TOKEN>")

# Prepare the Actor input
run_input = { "sponsors": [
        "Moderna",
        "Vertex Pharmaceuticals",
    ] }

# Run the Actor and wait for it to finish
run = client.actor("datasignalslab/biotech-catalyst-monitor").call(run_input=run_input)

# Fetch and print Actor results from the run's dataset (if there are any)
print("💾 Check your data here: https://console.apify.com/storage/datasets/" + run["defaultDatasetId"])
for item in client.dataset(run["defaultDatasetId"]).iterate_items():
    print(item)

# 📚 Want to learn more 📖? Go to → https://docs.apify.com/api/client/python/docs/quick-start

```

## CLI example

```bash
echo '{
  "sponsors": [
    "Moderna",
    "Vertex Pharmaceuticals"
  ]
}' |
apify call datasignalslab/biotech-catalyst-monitor --silent --output-dataset

```

## MCP server setup

```json
{
    "mcpServers": {
        "apify": {
            "command": "npx",
            "args": [
                "mcp-remote",
                "https://mcp.apify.com/?tools=datasignalslab/biotech-catalyst-monitor",
                "--header",
                "Authorization: Bearer <YOUR_API_TOKEN>"
            ]
        }
    }
}

```

## OpenAPI specification

```json
{
    "openapi": "3.0.1",
    "info": {
        "title": "Biotech Catalyst Monitor - Clinical Trial Readouts & Signals",
        "description": "Track upcoming clinical trial readouts, phase transitions and results from ClinicalTrials.gov, scored by stock-moving impact. A self-serve catalyst signal for biotech investors and traders.",
        "version": "0.1",
        "x-build-id": "3tkHQXf81ySODX0SV"
    },
    "servers": [
        {
            "url": "https://api.apify.com/v2"
        }
    ],
    "paths": {
        "/acts/datasignalslab~biotech-catalyst-monitor/run-sync-get-dataset-items": {
            "post": {
                "operationId": "run-sync-get-dataset-items-datasignalslab-biotech-catalyst-monitor",
                "x-openai-isConsequential": false,
                "summary": "Executes an Actor, waits for its completion, and returns Actor's dataset items in response.",
                "tags": [
                    "Run Actor"
                ],
                "requestBody": {
                    "required": true,
                    "content": {
                        "application/json": {
                            "schema": {
                                "$ref": "#/components/schemas/inputSchema"
                            }
                        }
                    }
                },
                "parameters": [
                    {
                        "name": "token",
                        "in": "query",
                        "required": true,
                        "schema": {
                            "type": "string"
                        },
                        "description": "Enter your Apify token here"
                    }
                ],
                "responses": {
                    "200": {
                        "description": "OK"
                    }
                }
            }
        },
        "/acts/datasignalslab~biotech-catalyst-monitor/runs": {
            "post": {
                "operationId": "runs-sync-datasignalslab-biotech-catalyst-monitor",
                "x-openai-isConsequential": false,
                "summary": "Executes an Actor and returns information about the initiated run in response.",
                "tags": [
                    "Run Actor"
                ],
                "requestBody": {
                    "required": true,
                    "content": {
                        "application/json": {
                            "schema": {
                                "$ref": "#/components/schemas/inputSchema"
                            }
                        }
                    }
                },
                "parameters": [
                    {
                        "name": "token",
                        "in": "query",
                        "required": true,
                        "schema": {
                            "type": "string"
                        },
                        "description": "Enter your Apify token here"
                    }
                ],
                "responses": {
                    "200": {
                        "description": "OK",
                        "content": {
                            "application/json": {
                                "schema": {
                                    "$ref": "#/components/schemas/runsResponseSchema"
                                }
                            }
                        }
                    }
                }
            }
        },
        "/acts/datasignalslab~biotech-catalyst-monitor/run-sync": {
            "post": {
                "operationId": "run-sync-datasignalslab-biotech-catalyst-monitor",
                "x-openai-isConsequential": false,
                "summary": "Executes an Actor, waits for completion, and returns the OUTPUT from Key-value store in response.",
                "tags": [
                    "Run Actor"
                ],
                "requestBody": {
                    "required": true,
                    "content": {
                        "application/json": {
                            "schema": {
                                "$ref": "#/components/schemas/inputSchema"
                            }
                        }
                    }
                },
                "parameters": [
                    {
                        "name": "token",
                        "in": "query",
                        "required": true,
                        "schema": {
                            "type": "string"
                        },
                        "description": "Enter your Apify token here"
                    }
                ],
                "responses": {
                    "200": {
                        "description": "OK"
                    }
                }
            }
        }
    },
    "components": {
        "schemas": {
            "inputSchema": {
                "type": "object",
                "required": [
                    "sponsors"
                ],
                "properties": {
                    "sponsors": {
                        "title": "Companies / trial sponsors",
                        "type": "array",
                        "description": "One or more biotech/pharma company names (trial sponsors), e.g. Moderna, Vertex Pharmaceuticals, BioNTech. Each is scanned for stock-moving trial catalysts.",
                        "items": {
                            "type": "string"
                        }
                    },
                    "maxStudies": {
                        "title": "Max studies per company",
                        "minimum": 1,
                        "maximum": 100,
                        "type": "integer",
                        "description": "How many of the company's trials to scan and rank.",
                        "default": 50
                    },
                    "minImpact": {
                        "title": "Minimum impact score (0-100)",
                        "minimum": 0,
                        "maximum": 100,
                        "type": "integer",
                        "description": "Only return catalysts at or above this impact score (e.g. 70 = high-impact: Phase 3 readouts, results). 0 = all.",
                        "default": 0
                    }
                }
            },
            "runsResponseSchema": {
                "type": "object",
                "properties": {
                    "data": {
                        "type": "object",
                        "properties": {
                            "id": {
                                "type": "string"
                            },
                            "actId": {
                                "type": "string"
                            },
                            "userId": {
                                "type": "string"
                            },
                            "startedAt": {
                                "type": "string",
                                "format": "date-time",
                                "example": "2025-01-08T00:00:00.000Z"
                            },
                            "finishedAt": {
                                "type": "string",
                                "format": "date-time",
                                "example": "2025-01-08T00:00:00.000Z"
                            },
                            "status": {
                                "type": "string",
                                "example": "READY"
                            },
                            "meta": {
                                "type": "object",
                                "properties": {
                                    "origin": {
                                        "type": "string",
                                        "example": "API"
                                    },
                                    "userAgent": {
                                        "type": "string"
                                    }
                                }
                            },
                            "stats": {
                                "type": "object",
                                "properties": {
                                    "inputBodyLen": {
                                        "type": "integer",
                                        "example": 2000
                                    },
                                    "rebootCount": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "restartCount": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "resurrectCount": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "computeUnits": {
                                        "type": "integer",
                                        "example": 0
                                    }
                                }
                            },
                            "options": {
                                "type": "object",
                                "properties": {
                                    "build": {
                                        "type": "string",
                                        "example": "latest"
                                    },
                                    "timeoutSecs": {
                                        "type": "integer",
                                        "example": 300
                                    },
                                    "memoryMbytes": {
                                        "type": "integer",
                                        "example": 1024
                                    },
                                    "diskMbytes": {
                                        "type": "integer",
                                        "example": 2048
                                    }
                                }
                            },
                            "buildId": {
                                "type": "string"
                            },
                            "defaultKeyValueStoreId": {
                                "type": "string"
                            },
                            "defaultDatasetId": {
                                "type": "string"
                            },
                            "defaultRequestQueueId": {
                                "type": "string"
                            },
                            "buildNumber": {
                                "type": "string",
                                "example": "1.0.0"
                            },
                            "containerUrl": {
                                "type": "string"
                            },
                            "usage": {
                                "type": "object",
                                "properties": {
                                    "ACTOR_COMPUTE_UNITS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "DATASET_READS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "DATASET_WRITES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "KEY_VALUE_STORE_READS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "KEY_VALUE_STORE_WRITES": {
                                        "type": "integer",
                                        "example": 1
                                    },
                                    "KEY_VALUE_STORE_LISTS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "REQUEST_QUEUE_READS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "REQUEST_QUEUE_WRITES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "DATA_TRANSFER_INTERNAL_GBYTES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "DATA_TRANSFER_EXTERNAL_GBYTES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "PROXY_RESIDENTIAL_TRANSFER_GBYTES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "PROXY_SERPS": {
                                        "type": "integer",
                                        "example": 0
                                    }
                                }
                            },
                            "usageTotalUsd": {
                                "type": "number",
                                "example": 0.00005
                            },
                            "usageUsd": {
                                "type": "object",
                                "properties": {
                                    "ACTOR_COMPUTE_UNITS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "DATASET_READS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "DATASET_WRITES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "KEY_VALUE_STORE_READS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "KEY_VALUE_STORE_WRITES": {
                                        "type": "number",
                                        "example": 0.00005
                                    },
                                    "KEY_VALUE_STORE_LISTS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "REQUEST_QUEUE_READS": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "REQUEST_QUEUE_WRITES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "DATA_TRANSFER_INTERNAL_GBYTES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "DATA_TRANSFER_EXTERNAL_GBYTES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "PROXY_RESIDENTIAL_TRANSFER_GBYTES": {
                                        "type": "integer",
                                        "example": 0
                                    },
                                    "PROXY_SERPS": {
                                        "type": "integer",
                                        "example": 0
                                    }
                                }
                            }
                        }
                    }
                }
            }
        }
    }
}
```
