# ClinicalTrials.gov API — clinical studies search (no key) (`synthetic.ia/clinicaltrials-api`) Actor

Search 500k+ clinical studies by condition, intervention, sponsor, location and status, and fetch full study detail by NCT id (summary, eligibility, outcomes, sponsor, locations). Official ClinicalTrials.gov v2 data. Clean HTTP API + MCP, no key. Pay per query.

- **URL**: https://apify.com/synthetic.ia/clinicaltrials-api.md
- **Developed by:** [Synthetic](https://apify.com/synthetic.ia) (community)
- **Stats:** 1 total users, 0 monthly users, 0.0% runs succeeded, 0 bookmarks
- **User rating**: No ratings yet

## Pricing

from $2.00 / 1,000 clinicaltrials queries

This Actor is paid per event and usage. You are charged both the fixed price for specific events and for Apify platform usage.
Since this Actor supports Apify Store discounts, the price gets lower the higher subscription plan you have.

Learn more: https://docs.apify.com/actors/running/actors-in-store.md#pay-per-event

## What's an Apify Actor?

An Actor is a serverless cloud program that runs on the Apify platform. It has two run modes.
In Batch mode, an Actor accepts a well-defined JSON input, performs an action which can take anything from a few seconds to a few hours,
and optionally produces a well-defined JSON output, datasets with results, or files in key-value store.
In Standby mode, an Actor provides a web server which can be used as a website, API, or an MCP server.

Apify vocabulary and the platform model are defined once, in the agent quickstart at https://apify.com/agents.md.

## How to integrate an Actor?

If asked about integration, you help developers integrate Actors into their projects.
You adapt to their stack and deliver integrations that are safe, well-documented, and production-ready.

Do not guess an integration path. Every one of them is in the agent quickstart at https://apify.com/agents.md: the Apify MCP server, Agent Skills with the Apify CLI, the JavaScript and Python clients, the REST API, and the account-free path for an agent with no human to sign in. It also carries the rule on stating cost before the first paid run.

For examples already wired to this Actor's own input schema, see the [API](#api) section below.

Each client library has reference documentation the quickstart does not restate: [JavaScript/TypeScript](https://docs.apify.com/api/client/js/docs.md) (`npm install apify-client`) and [Python](https://docs.apify.com/api/client/python/docs.md) (`pip install apify-client`).

# README

## ClinicalTrials.gov API — clinical studies search (no key)

Search the **official ClinicalTrials.gov** registry — **500,000+ clinical studies** — behind a clean HTTP API (and MCP tool). Find trials by **condition**, **intervention/drug**, **sponsor**, **location** and **recruitment status**, and pull **full study detail** by NCT id (summary, eligibility, outcomes, arms, sponsor, locations). Built for pharma & biotech research, health tech, patient tools, journalism and agents. **No API key.** Pay per query.

- 🔎 **Search** — by condition, intervention, sponsor, location and status; sort by relevance or most-recently-updated.
- 🧪 **Study detail** — NCT id → brief summary, phases, eligibility (sex, age, healthy volunteers), primary outcomes, arms, sponsor, collaborators, locations.
- 🏥 **Recruitment status** — filter for RECRUITING, COMPLETED, TERMINATED and more.
- 🇺🇸 **Official & keyless** — straight from ClinicalTrials.gov's v2 API.
- 💵 Pay per query.

### The use case it was built for

"Which recruiting trials target NASH, and who's sponsoring them?" — one call returns clean, typed rows; another returns the full protocol for a specific NCT. Perfect for competitive intelligence, patient-matching, systematic reviews and health agents.

### Sample output (`search`, condition "diabetes", status RECRUITING)

```json
{
  "ok": true, "totalCount": 1956, "count": 1,
  "studies": [
    { "nctId": "NCT07758582", "title": "Validation of the AI Subsystem of the D…",
      "status": "RECRUITING", "phases": [], "conditions": ["Diabetic Retinopathy"],
      "interventions": ["…"], "leadSponsor": "…", "locationsCount": 3,
      "url": "https://clinicaltrials.gov/study/NCT07758582" }
  ]
}
```

### How to use

- **HTTP API (Standby):** POST or GET `/search`, `/study`. `GET /` returns help. Example: `GET /search?condition=melanoma&status=RECRUITING`.
- **Normal run:** pass `{ operation, condition | nctId, ... }`; results land in the dataset + key-value store.
- **MCP tool:** expose it to your agent via Apify's MCP server.

### Input

- **operation** — `search` · `study`.
- **condition** / **intervention** / **term** / **sponsor** / **location** — search filters (combine any).
- **status** — recruitment statuses (e.g. `["RECRUITING"]`). **sort** — relevance / recent. **limit** — cap studies.
- **nctId** — for `study` (e.g. `NCT00841061`).

### Pricing

**Per query** from **$0.005** (down to $0.0015 on higher tiers). One call = one query (search returns many studies at once).

### Related Actors

- **[openFDA Drugs](https://apify.com/synthetic.ia/openfda-drugs)** — drug labels, adverse events and recalls.
- **[Crossref API](https://apify.com/synthetic.ia/crossref-scholar-api)** — scholarly papers and DOI metadata.

### FAQ

**Do I need a key?** No — ClinicalTrials.gov's v2 API is keyless.

**Which statuses can I filter by?** RECRUITING, NOT\_YET\_RECRUITING, ACTIVE\_NOT\_RECRUITING, COMPLETED, ENROLLING\_BY\_INVITATION, SUSPENDED, TERMINATED, WITHDRAWN and more.

**How fresh is the data?** ClinicalTrials.gov is updated continuously as sponsors submit and revise records.

### Notes & limits

Data from the U.S. National Library of Medicine's ClinicalTrials.gov (api v2). Up to 100 studies per search call; use filters to focus. This is registry metadata, not medical advice.

# Changelog

This Actor's version history is a separate document: https://apify.com/synthetic.ia/clinicaltrials-api/changelog.md

# Actor input Schema

## `operation` (type: `string`):

What to do.

## `condition` (type: `string`):

e.g. diabetes, breast cancer.

## `intervention` (type: `string`):

e.g. metformin, semaglutide.

## `term` (type: `string`):

Any other keywords.

## `sponsor` (type: `string`):

Lead sponsor / organization, e.g. Pfizer.

## `location` (type: `string`):

Country or city, e.g. Argentina.

## `status` (type: `array`):

Filter by status, e.g. RECRUITING. Leave empty for all.

## `sort` (type: `string`):

Result ordering.

## `nctId` (type: `string`):

e.g. NCT00841061.

## `limit` (type: `integer`):

Max studies (≤100).

## Actor input object example

```json
{
  "operation": "search",
  "condition": "diabetes",
  "status": [
    "RECRUITING"
  ],
  "sort": "relevance",
  "limit": 15
}
```

# Actor output Schema

## `result` (type: `string`):

No description

## `runs` (type: `string`):

No description

# API

You can run this Actor programmatically using our API. Below are code examples in JavaScript, Python, and CLI, as well as the OpenAPI specification and MCP server setup.

## JavaScript example

```javascript
import { ApifyClient } from 'apify-client';

// Initialize the ApifyClient with your Apify API token
// Replace the '<YOUR_API_TOKEN>' with your token
const client = new ApifyClient({
    token: '<YOUR_API_TOKEN>',
});

// Prepare Actor input
const input = {
    "condition": "diabetes",
    "status": [
        "RECRUITING"
    ]
};

// Run the Actor and wait for it to finish
const run = await client.actor("synthetic.ia/clinicaltrials-api").call(input);

// Fetch and print Actor results from the run's dataset (if any)
console.log('Results from dataset');
console.log(`💾 Check your data here: https://console.apify.com/storage/datasets/${run.defaultDatasetId}`);
const { items } = await client.dataset(run.defaultDatasetId).listItems();
items.forEach((item) => {
    console.dir(item);
});

// 📚 Want to learn more 📖? Go to → https://docs.apify.com/api/client/js/docs

```

## Python example

```python
from apify_client import ApifyClient

# Initialize the ApifyClient with your Apify API token
# Replace '<YOUR_API_TOKEN>' with your token.
client = ApifyClient("<YOUR_API_TOKEN>")

# Prepare the Actor input
run_input = {
    "condition": "diabetes",
    "status": ["RECRUITING"],
}

# Run the Actor and wait for it to finish
run = client.actor("synthetic.ia/clinicaltrials-api").call(run_input=run_input)

# Fetch and print Actor results from the run's dataset (if there are any)
print(f"💾 Check your data here: https://console.apify.com/storage/datasets/{run.default_dataset_id}")
for item in client.dataset(run.default_dataset_id).iterate_items():
    print(item)

# 📚 Want to learn more 📖? Go to → https://docs.apify.com/api/client/python/docs/quick-start

```

## CLI example

```bash
echo '{
  "condition": "diabetes",
  "status": [
    "RECRUITING"
  ]
}' |
apify call synthetic.ia/clinicaltrials-api --silent --output-dataset

```

## MCP server setup

```json
{
    "mcpServers": {
        "apify": {
            "type": "http",
            "url": "https://mcp.apify.com/?tools=fetch-actor-details,synthetic.ia/clinicaltrials-api"
        }
    }
}
```

The hosted server signs you in with OAuth on first connect, so no API token belongs in this config. Clients without OAuth support can send an `Authorization: Bearer <APIFY_API_TOKEN>` header instead, using a token from API & Integrations in Apify Console (https://console.apify.com/settings/integrations).

## OpenAPI specification

Download the OpenAPI definition: https://api.apify.com/v2/actors/4kgAtmXNMccqaSymS/builds/U0agSiAliwTEciucO/openapi.json