PubMed & ClinicalTrials MCP Server — Biomedical AI avatar

PubMed & ClinicalTrials MCP Server — Biomedical AI

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PubMed & ClinicalTrials MCP Server — Biomedical AI

PubMed & ClinicalTrials MCP Server — Biomedical AI

MCP server providing AI agents with access to PubMed (37M+ articles) and ClinicalTrials.gov (500K+ studies). Search biomedical literature, fetch abstracts, and find clinical trials with structured data. Supports date filtering, status filtering, and batch PMID lookups.

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Pay per usage

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kettledrum

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PubMed & ClinicalTrials.gov MCP Server

MCP (Model Context Protocol) server providing AI agents with direct access to 37M+ PubMed articles and 500K+ clinical trials from ClinicalTrials.gov — two official NIH data sources in one server.

Connect any MCP-compatible client (Claude Desktop, Cursor, Cline, etc.) to search medical research and clinical studies.

Tools

ToolDescription
search_pubmedSearch PubMed articles by keyword, with full abstracts
get_article_abstractsFetch abstracts for specific PMIDs
search_clinical_trialsSearch ClinicalTrials.gov studies
get_article_detailsGet detailed metadata for a PubMed article

Connect via MCP

Claude Desktop / Cursor

{
"mcpServers": {
"pubmed": {
"url": "https://aligned-kettledrum--pubmed-mcp-server.apify.actor/mcp",
"headers": {
"Authorization": "Bearer YOUR_APIFY_TOKEN"
}
}
}
}

Using mcp-remote (npx)

npx mcp-remote https://aligned-kettledrum--pubmed-mcp-server.apify.actor/mcp \
--header "Authorization: Bearer YOUR_APIFY_TOKEN"

Example Queries

Once connected, ask your AI assistant:

  • "Find recent papers about CRISPR gene editing in cancer therapy"
  • "Search for clinical trials on GLP-1 receptor agonists for obesity"
  • "Get the abstract for PMID 37198476"
  • "What are the latest Phase 3 trials for Alzheimer's disease?"

Data Source

  • PubMed: NCBI E-utilities API — 37M+ biomedical articles from 5,200+ journals
  • ClinicalTrials.gov: v2 API — 500K+ clinical studies worldwide

Both APIs are maintained by the U.S. National Institutes of Health. Free, no API key required.

FAQ

Q: Do I need an API key? A: No. Both PubMed and ClinicalTrials.gov APIs are free and open.

Q: How current is the data? A: PubMed indexes new articles within days of publication. ClinicalTrials.gov updates are near real-time as sponsors submit data.

Q: Can I get full-text articles? A: This server provides abstracts and metadata. Full-text access depends on publisher open-access policies.

Q: Is there a rate limit? A: The server handles NCBI's rate limiting (3 req/sec) automatically. No client-side throttling needed.

Batch Processing

For large-scale data extraction (thousands of articles), use the PubMed & ClinicalTrials.gov Actor which supports bulk downloads with pagination.