ClinicalTrials Monitor: New Trials & Status Changes (MCP)

Every clinical trial on Earth — 500,000+ studies from the official ClinicalTrials.gov API v2, no key, no login. Search by condition, drug or sponsor-side filters; pull a full trial by NCT id; or watch terms and get alerted on new trials and the moment a study flips RECRUITING → COMPLETED → TERMINATED. MCP-compatible, agent-ready.

Who pays for this data

Pharmaceutical ops teams, CROs, medical writers, investors' research desks, patient-recruitment agencies and university labs all monitor the registry — usually by hand. Status changes matter: a big trial going COMPLETED means results are coming; TERMINATED means a competitor's candidate just died. This actor turns that ritual into a schedule + a webhook.

What you get per row

nctId, briefTitle, overallStatus, phase, studyType, conditions, interventions (drugs/devices), leadSponsor + sponsorClass (INDUSTRY/OTHER), enrollmentCount & type (ACTUAL/ESTIMATED), startDate / primaryCompletion / completionDate, lastUpdate, age limits, sex, location countries, and the direct trial URL.

Three modes

search — find studies

{ "mode": "search", "query": "semaglutide", "status": "RECRUITING", "country": "Germany", "phase": "3", "maxResults": 10 }

trial — one study, full record

{ "mode": "trial", "nctId": "NCT07212530" }

monitor — never miss a move

{ "mode": "monitor", "watchQueries": ["diabetes", "tirzepatide|RECRUITING@United States"], "maxResults": 20 }

• Run 1 = free baseline — snapshot of the latest-updated studies for each watch query.
• Run 2+ emits only: new-trial (within your tracked set: appeared in the latest-updated sample) and status-changed (with old → new in info).
• Schedule daily; a quiet day costs $0.001 (start only).

Data honesty & limits

• Every field comes from the official ClinicalTrials.gov API at run time; estimated dates are marked by the source (we surface the enrollment type so you can tell ESTIMATED from ACTUAL).
• Monitor covers the most recently updated studies per watch query (top 60 sorted by last-updated) — deep-archive sweeps belong to search mode. Say a popular condition like "diabetes" gets hundreds of updates per day: raise the sample by splitting watches (diabetes|RECRUITING@France …) for full coverage.
• No adverse-event narratives, no results-section parsing — those live in separate endpoints and can be added on request (Issues tab).

Recipes

1. Pipeline radar for pharma BD — watch a competitor's drug name; get pinged when a phase-3 trial posts or completes.
2. Patient recruitment — agents find RECRUITING trials in a country for a condition and hand the rows to outreach.
3. Literature/med-writer brief — search a condition, export the last-N updated records with sponsor and enrollment.

Pricing

event	price
Actor start	$0.001
Clinical trial record	$0.001 / row

Typical runs: enriched 10-row search ≈ $0.011 · daily monitor with 2 changes ≈ $0.003.

MCP / AI-agent usage

https://api.apify.com/v2/acts/YOUR_HANDLE~clinical-trials-monitor/run-sync-get-dataset-items?token=YOUR_TOKEN

Input = the JSON examples above. Output = rows as documented. Compatible with per-request agentic payments.

Questions / module requests (results, references, adverse events): Issues tab on Apify Store.