Drug Safety Intelligence — FDA + Clinical Trials + PubMed

The only drug safety Actor that combines FDA enforcement data with active clinical trial status and scientific research attention — three US government sources in a single call, zero API keys required.

What it does

A complete drug intelligence profile needs three layers: what the FDA knows about safety incidents, what researchers are actively testing, and how much scientific attention this compound gets. This Actor fetches all three in parallel and synthesizes them into a single structured output.

Source	Data	License
OpenFDA	Adverse events, recalls, label data	CC0 Public Domain
ClinicalTrials.gov	Active recruiting and ongoing trials	NIH Public Domain
NCBI PubMed	Total publications + 5-year research trend	NLM Public Domain

Input

{
  "drugName": "aspirin",
  "maxResults": 10
}

Field	Type	Default	Description
drugName	string	"aspirin"	Brand name, generic name, or active ingredient
maxResults	number	10	Max adverse events / recalls to return (up to 100)

Output

{
  "drugName": "metformin",
  "summary": {
    "totalAdverseEvents": 45821,
    "totalRecalls": 12,
    "totalLabels": 38,
    "activeTrials": 127,
    "totalPublications": 28943,
    "safetyRisk": "MEDIUM",
    "researchActivity": "HIGH",
    "researchAttention": "VERY_HIGH"
  },
  "topAdverseReactions": [
    { "reaction": "nausea", "count": 3241 },
    { "reaction": "diarrhoea", "count": 2876 }
  ],
  "recentRecalls": [
    {
      "recallNumber": "D-0123-2024",
      "date": "20240315",
      "reason": "NDMA contamination above acceptable daily intake",
      "status": "Ongoing",
      "classification": "Class II"
    }
  ],
  "clinicalResearch": {
    "totalActiveTrials": 127,
    "activityLevel": "HIGH",
    "trials": [
      {
        "nctId": "NCT05123456",
        "title": "Metformin in Early-Stage Pancreatic Cancer",
        "phase": "Phase 2",
        "status": "RECRUITING",
        "enrollment": 240
      }
    ]
  },
  "scientificLiterature": {
    "totalPublications": 28943,
    "recentPublications5yr": 9821,
    "recentPublicationsPercent": "34%",
    "researchAttention": "VERY_HIGH",
    "researchTrend": "ACTIVE",
    "source": "NCBI PubMed (National Library of Medicine, Public Domain)"
  }
}

Use Cases

• Pharma competitive intelligence — compare pipeline activity and publication velocity across compounds
• Drug safety monitoring — automated recall and adverse event alerts for compliance teams
• Healthcare procurement — safety risk assessment before formulary decisions
• Medical research tools — surface which drugs have high scientific interest but few active trials
• Insurance underwriting — risk profiling for drug liability policies

Why this beats building it yourself

Three separate API integrations (FDA, ClinicalTrials, PubMed), different query formats, parallel fetching, and result synthesis. This Actor delivers a unified profile in under 10 seconds.

Attribution

This product uses the openFDA API but is not endorsed by the FDA or the US Federal Government.

• OpenFDA: https://open.fda.gov
• ClinicalTrials.gov: https://clinicaltrials.gov
• NCBI PubMed: https://pubmed.ncbi.nlm.nih.gov