ClinicalTrials.gov API & Scraper – Clinical Trials by Condition, Sponsor, Phase and Update Date

A clinical trials API for the ClinicalTrials.gov registry (500,000+ studies worldwide), built on its official API v2, for searching trials and tracking pharma pipelines. One flat row per trial: status, phase, study type, conditions, interventions, lead sponsor and class, collaborators, enrollment, design, start and completion dates, first-posted and last-updated dates, results flag, eligibility (sex, age, healthy volunteers, criteria text), site locations by facility, city and country, and the study URL.

Built for pharma and biotech competitive intelligence, CROs and clinical operations, market researchers, investors following pipelines, patient advocacy groups and data journalists who need a condition, a sponsor or a therapeutic area watched every day.

Why this one

• Official API v2, no key, no login. One request returns up to 1,000 studies. Runs take seconds.
• Daily monitoring built in. updatedAfter (last-update date) and firstPostedAfter (new registrations) use the registry's own dates. A daily schedule with "yesterday" returns only what changed.
• Honest to the terms of use. Each row carries source (ClinicalTrials.gov) and dataProcessedAt, the date ClinicalTrials.gov processed the data, as its terms require. See Data source and attribution below. Names, phones and e-mails of investigators and contacts are deliberately left out; you get organizations, facilities and places.
• Pay per study, from the first row. No 100-row cap for free accounts, no start fee, no charge for empty runs or error rows.

Pricing

$3.00 per 1,000 studies (event study). That is 1,000 fully flattened trials for the price of a coffee; comparable actors charge $8–12 per 1,000. Apify's free plan ($5 monthly credit) covers about 1,600 studies per month. Cap spend with maxItems and the run's Maximum total charge.

Input

Field	Type	Default	Description
condition	string		Condition or disease (query.cond), e.g. diabetes, breast cancer.
intervention	string		Drug, device or procedure (query.intr), e.g. semaglutide.
term	string		Free text over the whole record (query.term).
sponsor	string		Sponsor or collaborator name (query.spons), e.g. Pfizer.
location	string		City, state or country of sites (query.locn).
status	array	[]	RECRUITING, NOT_YET_RECRUITING, ACTIVE_NOT_RECRUITING, COMPLETED, TERMINATED, … Empty = any.
phase	array	[]	EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA.
studyType	string	any	INTERVENTIONAL, OBSERVATIONAL, EXPANDED_ACCESS.
updatedAfter	string		YYYY-MM-DD. Records last updated on or after this date.
firstPostedAfter	string		YYYY-MM-DD. Records first posted on or after this date.
sort	string	LastUpdatePostDate:desc	Or StudyFirstPostDate:desc, relevance.
maxItems	integer	100	Stop after this many studies.
minResults	integer		Monitoring only: fail the run if fewer studies are returned.

At least one filter is required (the whole registry is not a query).

Competitor pipeline watch, Phase 3 trials by one sponsor changed since yesterday:

{ "sponsor": "Novo Nordisk", "phase": ["PHASE3"], "updatedAfter": "2026-10-25", "maxItems": 500 }

Recruiting trials for a condition in one country:

{ "condition": "alzheimer", "status": ["RECRUITING", "NOT_YET_RECRUITING"], "location": "Germany", "maxItems": 1000 }

Output

{
    "nctId": "NCT07573462",
    "url": "https://clinicaltrials.gov/study/NCT07573462",
    "title": "A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine",
    "officialTitle": "A PHASE 3, RANDOMIZED, DOUBLE-BLINDED TRIAL TO EVALUATE ...",
    "acronym": null,
    "organization": "Pfizer",
    "status": "RECRUITING",
    "statusVerifiedDate": "2026-10",
    "studyType": "INTERVENTIONAL",
    "phases": ["PHASE3"],
    "conditions": ["Pneumococcal Disease"],
    "keywords": [],
    "interventions": [{ "type": "BIOLOGICAL", "name": "PG4" }],
    "leadSponsor": "Pfizer",
    "leadSponsorClass": "INDUSTRY",
    "collaborators": [],
    "enrollment": 2400,
    "enrollmentType": "ESTIMATED",
    "allocation": "RANDOMIZED",
    "masking": "QUADRUPLE",
    "primaryPurpose": "PREVENTION",
    "startDate": "2026-05-04",
    "primaryCompletionDate": "2028-12-30",
    "completionDate": "2028-12-30",
    "firstPosted": "2026-05-07",
    "lastUpdatePosted": "2026-10-26",
    "resultsFirstPosted": null,
    "hasResults": false,
    "sex": "ALL",
    "minimumAge": "42 Days",
    "maximumAge": "98 Days",
    "stdAges": ["CHILD"],
    "healthyVolunteers": true,
    "eligibilityCriteria": "Inclusion Criteria: ...",
    "briefSummary": "The purpose of this study is ...",
    "locationsCount": 78,
    "countries": ["United States", "Argentina", "Australia", "Canada"],
    "locations": [{ "facility": "Clinical Research Site", "city": "Buenos Aires", "state": null, "country": "Argentina", "status": "RECRUITING" }],
    "dataProcessedAt": "2026-10-26T09:00:04",
    "dataProcessedAtSource": "ClinicalTrials.gov API dataTimestamp",
    "source": "ClinicalTrials.gov",
    "scrapedAt": "2026-10-26T13:49:53.496Z"
}

Dates are as published (some are month-only, e.g. 2026-10). Missing data is null, never invented. A run with no match writes one { "error": true, "errorType": "NO_RESULTS", ... } row; invalid input writes an INVALID_INPUT row. Neither is charged.

Data source and attribution

Source: ClinicalTrials.gov, a database of the U.S. National Library of Medicine (National Institutes of Health). Data obtained through the ClinicalTrials.gov API v2. This Actor is not affiliated with or endorsed by NLM, NIH or HHS, and ClinicalTrials.gov makes no warranties about the data.

Date processed by ClinicalTrials.gov: every row includes dataProcessedAt, taken from the dataTimestamp the API publishes at run time (the registry is refreshed on business days). If the API ever omits it, the field holds the collection time and dataProcessedAtSource says so. Re-run the Actor to keep your copy current.

Modifications made to the data:

• Each study record is flattened into one row; nested modules are reduced to the fields listed in Output.
• Central contacts, overall officials and the responsible party (names, phones, e-mails of people) are removed.
• Outcome measures, adverse events and other results sections are not included; hasResults and resultsFirstPosted indicate they exist.
• Site locations keep facility, city, state, country and recruitment status; geocoordinates and site contacts are removed.
• Text fields (summary, eligibility criteria) and dates are passed through as published, without editing.

If you publish or redistribute this data, attribute it to ClinicalTrials.gov, show dataProcessedAt, and state these modifications.

Use it from code

curl -X POST "https://api.apify.com/v2/acts/opentenders~clinicaltrials-scraper/run-sync-get-dataset-items?format=json" \
  -H "Authorization: Bearer $APIFY_TOKEN" -H "Content-Type: application/json" \
  -d '{"condition":"melanoma","status":["RECRUITING"],"phase":["PHASE2","PHASE3"],"maxItems":200}'

Works with the Apify API, clients, MCP server, Make, Zapier, n8n and Google Sheets integrations.

Limitations

• Data is what sponsors register. Enrollment, dates and sites can be outdated or missing; dataProcessedAt tells you the registry snapshot.
• Investigator and contact details are intentionally not returned.
• Requests are made one at a time to respect the registry (1,000 studies per request, so 10,000 studies take about 15 seconds).
• Results data (outcome measures, adverse events) are not included; hasResults and resultsFirstPosted tell you when they exist.

FAQ

Is this allowed? Yes. ClinicalTrials.gov data is available to all requesters at no charge through its public API. Its terms ask for attribution, the processing date and a statement of modifications; see Data source and attribution.

How do I get only new trials? Use firstPostedAfter for brand-new registrations and updatedAfter for any change (status, enrollment, sites). Schedule daily with yesterday's date.

Can I search by NCT ID? Put the IDs in term, e.g. NCT07573462 OR NCT06704672.

Something broke? Open an issue with the run ID; the actor fails with the exact API response when ClinicalTrials.gov changes.