NCBI Human Gene Symbol Lookup — Official Gene ID API

Resolve exact human gene symbols such as BRCA1, TP53, and EGFR against the official NCBI Gene database.

Use it for gene identifier resolution, bioinformatics preprocessing, research-data normalization, genomics datasets, symbol validation, and automated NCBI workflows.

Independent tool. Not affiliated with or endorsed by NCBI, NIH, or NLM. This is a data lookup utility, not medical or diagnostic advice.

Common use cases

• Resolve human gene symbols to canonical NCBI Gene IDs
• Validate symbols before joining genomics datasets
• Collect aliases, chromosome, map-location, and nomenclature fields
• Normalize gene identifiers for research pipelines
• Feed official gene records into downstream bioinformatics workflows

What you get

One row per submitted symbol when a canonical human gene is found, including NCBI Gene ID, official symbol and name, description, organism/taxonomy ID, chromosome and map location, aliases, other designations, nomenclature status, source URL, and capture timestamp.

Try it

{
  "symbols": ["BRCA1", "TP53", "EGFR"]
}

Source and request policy

Uses official NCBI Entrez E-utilities with tool and email parameters. NCBI permits up to 3 requests/second without an API key. This Actor spaces requests below that ceiling and caps input at 40 symbols so a normal run remains bounded.

Important limitations

Exact symbols that do not resolve return non-billed not-found diagnostic rows.

This Actor resolves source records only. It does not interpret variants, diagnose disease, determine clinical significance, establish gene-disease causality, or provide medical advice.

Pricing

Only successfully resolved canonical gene rows are billed. Not-found diagnostics, zero-result summaries, and budget-limit summaries are free.

Candidate target: $0.25 per 1,000 resolved gene rows, subject to the live economics gate.

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