Clinical Trials Recruiting Change Monitor

Monitor ClinicalTrials.gov for recruiting-study changes instead of repeatedly exporting the same static list.

What it tracks

Each study includes the current sponsor, status, phase, enrollment, interventions, countries, central contacts, all reported sites and recruiting sites. Reuse the same stateKey on scheduled runs and the Actor compares the latest snapshot with the previous one.

Change signals include:

• NEW_TRIAL
• NEW_SITE
• SITE_REMOVED
• SITE_STARTED_RECRUITING
• SITE_STOPPED_RECRUITING
• STATUS_CHANGED
• SPONSOR_CHANGED
• ENROLLMENT_CHANGED

The row also includes previousStatus, previousSponsor, previousEnrollment, firstSeenAt, lastSeenAt and the affected site lists.

Search filters

You can combine:

• up to 10 conditions
• country and state/region
• sponsor/collaborator
• intervention/treatment
• study phases
• study statuses
• up to 250 results per condition

The source is the official ClinicalTrials.gov API v2. No proxy or account is required.

Monitoring modes

emitMode controls what is delivered and billed:

• all — all matching current studies
• new — only studies not seen before under the state key
• changed — only previously seen studies whose tracked fields changed
• new_or_changed — new studies plus changed studies, suppressing unchanged rows

For scheduled monitoring, new_or_changed is normally the useful mode. The older onlyNew input remains supported and maps to new_or_changed when emitMode is all.

Example:

{
  "conditions": ["lung cancer"],
  "country": "Germany",
  "phases": ["PHASE2", "PHASE3"],
  "statuses": ["RECRUITING", "NOT_YET_RECRUITING", "ACTIVE_NOT_RECRUITING"],
  "emitMode": "new_or_changed",
  "stateKey": "lung-cancer-germany",
  "limit": 100
}

Why the status list matters

The API only returns statuses you request. Keep both recruiting and nearby lifecycle statuses in the watchlist if you want to detect transitions such as RECRUITING to ACTIVE_NOT_RECRUITING. Add terminal statuses if you also want those studies returned by the query.

Pricing

The PPE event delivered-trial costs $0.0015 per delivered dataset row ($1.50 / 1,000). Rows suppressed by monitoring mode do not trigger the delivery event. Platform compute/storage can still be consumed by a run.

RUN_SUMMARY reports fetched, delivered, suppressed, new, changed and unchanged counts plus the active delivery mode.

ClinicalTrials.gov records are submitted by study sponsors/investigators and can change after retrieval. Always verify important details at the linked source record. This Actor is independent of and not endorsed by NLM or NIH and does not provide medical advice.