ClinicalTrials.gov Recruiting Trial Sites & Sponsors (API v2)

Extract recruiting clinical studies from the official ClinicalTrials.gov REST API v2 (https://clinicaltrials.gov/api/v2/studies), including lead sponsor details, clinical phases, conditions, interventions, target enrollment and the participating trial sites. Optionally (off by default) it also returns the study contacts published on ClinicalTrials.gov for each study and site.

Supports two output modes:

• Site-row mode (flattenSites: true, default): one row per matching clinical trial site (siteFacility, siteCity, siteState, siteCountry, and site-level contacts when includeSiteContacts is on), with study and sponsor metadata repeated on each row.
• Study-row mode (flattenSites: false): one row per study (nctId) with all matching trial locations nested under sites.

Who it's for

• CROs, patient recruitment vendors, eClinical / CTMS / EDC providers & specialty labs identifying active Industry-sponsored Phase 2 and Phase 3 studies and their participating clinical trial sites
• Biopharma business development & medical affairs teams tracking competing pipelines, sponsor classes (INDUSTRY, NIH, FED, OTHER), and investigating facilities by therapeutic area and state
• Clinical trial site networks &SMO teams monitoring newly updated recruiting trials across specific US states or countries

Input

All filters are optional. Default input pulls up to 200 US trial site rows from RECRUITING and NOT_YET_RECRUITING Industry-sponsored Phase 2 and Phase 3 clinical trials, most recently updated first. Only sites that are themselves recruiting or not yet recruiting are included, at most 20 sites per trial, and contact fields are off.

{
  "conditionOrDisease": "Non-Small Cell Lung Cancer",
  "interventionOrTreatment": "",
  "sponsorName": "",
  "overallStatuses": ["RECRUITING", "NOT_YET_RECRUITING"],
  "sponsorClass": "INDUSTRY",
  "phases": ["PHASE2", "PHASE3"],
  "updatedSinceDate": "2026-09-01",
  "flattenSites": true,
  "siteCountries": ["United States"],
  "siteStates": ["CA", "TX", "NY"],
  "siteStatuses": ["RECRUITING", "NOT_YET_RECRUITING"],
  "maxSitesPerTrial": 20,
  "includeSiteContacts": false,
  "maxItems": 200
}

Field	Type	Default	Description
conditionOrDisease	string	"" (all)	Condition or disease search (query.cond).
interventionOrTreatment	string	"" (all)	Drug, biological, device, or procedure query (query.intr).
sponsorName	string	"" (all)	Lead sponsor or collaborator query (query.spons).
overallStatuses	array	["RECRUITING", "NOT_YET_RECRUITING"]	Recruitment statuses (filter.overallStatus).
sponsorClass	string	"INDUSTRY"	INDUSTRY, NIH, FED, OTHER, or ALL.
phases	array	["PHASE2", "PHASE3"]	EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA.
updatedSinceDate	string (YYYY-MM-DD)	""	Minimum LastUpdatePostDate (AREA[LastUpdatePostDate]RANGE[<date>,MAX]).
flattenSites	boolean	true	Emit one row per matching study site (true) or one row per study (false).
siteCountries	array of strings	["United States"]	Filter trial locations by country name.
siteStates	array of strings	[] (all)	Filter trial locations by state/province (accepts both 2-letter US codes like "TX" and full names like "Texas").
siteStatuses	array	["RECRUITING", "NOT_YET_RECRUITING"]	Keep only sites with these site-level recruitment statuses. Empty list = all sites.
maxSitesPerTrial	integer	20	Maximum sites returned per trial, so one large trial doesn't fill the whole result. 0 = no cap.
includeSiteContacts	boolean	false	Also return central and site contact names, emails and phones as published on ClinicalTrials.gov. Read the compliance section first.
maxItems	integer	200	Maximum number of output rows.

Output

Field	Type	Description
nctId	string	ClinicalTrials.gov NCT identifier
briefTitle	string | null	Study brief title
overallStatus	string | null	Recruitment status (RECRUITING, NOT_YET_RECRUITING, etc.)
phases	array of strings	Clinical phases (PHASE2, PHASE3, etc.)
conditions	array of strings	Conditions or diseases studied
interventions	array of strings	Intervention names
enrollmentTarget	integer | null	Target or actual participant enrollment count
startDate	string | null	Study start date
lastUpdatePostDate	string | null	Last update posted date
leadSponsorName	string | null	Lead sponsor organization name
leadSponsorClass	string | null	Lead sponsor class (INDUSTRY, NIH, FED, OTHER)
centralContactName	string | null	Central published study contact name (as listed on ClinicalTrials.gov). Only with includeSiteContacts
centralContactEmail	string | null	Central published study contact email (as listed on ClinicalTrials.gov). Only with includeSiteContacts
centralContactPhone	string | null	Central published study contact phone (as listed on ClinicalTrials.gov). Only with includeSiteContacts
overallOfficial	string | null	Primary overall study official (Name (Role) - Affiliation). Only filled when includeSiteContacts is on; otherwise null.
overallOfficialRole	string | null	Role of the primary overall official (e.g. PRINCIPAL_INVESTIGATOR). Always included.
overallOfficialAffiliation	string | null	Affiliation of the primary overall official. Always included.
siteFacility	string | null	Trial site facility name
siteStatus	string | null	Site-specific recruitment status
siteCity	string | null	Trial site city
siteState	string | null	Trial site state or province
siteZip	string | null	Trial site postal/ZIP code
siteCountry	string | null	Trial site country
siteContactName	string | null	Site-level published study contact name (as listed on ClinicalTrials.gov). Only with includeSiteContacts
siteContactRole	string | null	Site-level published study contact role. Only with includeSiteContacts
siteContactEmail	string | null	Site-level published study contact email (as listed on ClinicalTrials.gov). Only with includeSiteContacts
siteContactPhone	string | null	Site-level published study contact phone (as listed on ClinicalTrials.gov). Only with includeSiteContacts
sites	array | null	Array of matching sites when flattenSites is false (null in site-row mode)
studyUrl	string	Direct URL: https://clinicaltrials.gov/study/<nctId>

Sample output row

{
  "nctId": "NCT07221669",
  "briefTitle": "A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)",
  "overallStatus": "RECRUITING",
  "phases": ["PHASE3"],
  "conditions": ["Muscular Atrophy, Spinal"],
  "interventions": ["Salanersen"],
  "enrollmentTarget": 30,
  "startDate": "2026-04-28",
  "lastUpdatePostDate": "2026-10-23",
  "leadSponsorName": "Biogen",
  "leadSponsorClass": "INDUSTRY",
  "centralContactName": null,
  "centralContactEmail": null,
  "centralContactPhone": null,
  "overallOfficial": null,
  "overallOfficialRole": "STUDY_DIRECTOR",
  "overallOfficialAffiliation": "Example Biotherapeutics",
  "studyUrl": "https://clinicaltrials.gov/study/NCT07221669",
  "siteFacility": "Ann and Robert H Lurie Childrens Hospital of Chicago",
  "siteStatus": "RECRUITING",
  "siteCity": "Chicago",
  "siteState": "Illinois",
  "siteZip": "60611",
  "siteCountry": "United States",
  "siteContactName": null,
  "siteContactRole": null,
  "siteContactEmail": null,
  "siteContactPhone": null,
  "sites": null
}

How pricing works

Pay per result. You only pay for rows returned.

Data source and terms

Source: ClinicalTrials.gov, a service of the U.S. National Library of Medicine (NLM), National Institutes of Health, via its REST API v2 (https://clinicaltrials.gov/api/v2/studies). ClinicalTrials.gov updates daily on federal business days; each row's lastUpdatePostDate is the date ClinicalTrials.gov last posted an update for that study. Use of the data is subject to the ClinicalTrials.gov Terms and Conditions.

Modified/derived data notice: this Actor does not change study content, but it reshapes it: it selects a subset of fields, flattens each study into one row per site (repeating study fields), keeps only the first central and site contact, filters sites by country/state/site status, caps sites per trial, and removes contact fields unless includeSiteContacts is on. For the authoritative, current record always check studyUrl. This Actor is not affiliated with or endorsed by NLM, NIH or ClinicalTrials.gov.

Compliance: contact data

• No unsolicited marketing. ClinicalTrials.gov's terms say email addresses from its database must not be used for marketing or promotional purposes. Contacts are published so patients and referring clinicians can ask about a study.
• CAN-SPAM and TCPA apply to any commercial email, call or text you send in the US. Don't autodial or text without the required consent.
• GDPR / UK GDPR and other privacy laws apply to contacts at non-US sites (and many named US contacts are personal data). You need a lawful basis to process them.
• Keep includeSiteContacts off unless you need contacts for a permitted purpose.

Limits and FAQ

• Why are siteContactName or siteContactEmail sometimes null? Large industry sponsors often publish a centralized trial hotline/email (centralContactName, centralContactEmail, centralContactPhone) while listing only facility names and phone numbers at individual sites, whereas academic and mid-size biotech trials more frequently list individual site coordinator names and emails. With includeSiteContacts on, both central and site-level contacts are included on every row.
• Can I pass 2-letter state codes like "CA" in siteStates? Yes. ClinicalTrials.gov stores full state names ("California") on US locations, and this Actor automatically matches both 2-letter US postal codes ("CA") and full state names ("California").

Changelog

• v0.1.2 — Contacts are off by default (includeSiteContacts). New siteStatuses filter (default recruiting / not yet recruiting) and maxSitesPerTrial cap (default 20). Added source attribution and a modified-data notice.

• v0.1.1 — Results are sorted by most recently updated study first.

• v0.1 — Initial release supporting ClinicalTrials.gov API v2 Essie advanced filters, automatic US state code/name matching, and site/study row modes.