ClinicalTrials.gov Study Monitor

This Actor extracts clinical study records from the official ClinicalTrials.gov API v2 (no key needed) for a condition, phase and status of your choice. It returns the studies whose status, phase, enrollment or last update changed since your last run. It is meant for patient-recruitment firms, CROs and biotech analysts who follow studies by condition on a schedule.

What you get

Each result is one study record with the NCT id, title, sponsor, phase, status, enrollment, start and completion dates, last update date, conditions, lead intervention and the country of the first listed location. It also carries previous (the earlier values of the watched fields when they changed) and first_seen (true the first time a study appears). The record is at clinicaltrials.gov/study/<nct_id>.

Example item from a real run:

{
  "nct_id": "NCT03596450",
  "title": "Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial",
  "sponsor": "Novo Nordisk A/S",
  "phase": ["PHASE4"],
  "status": "COMPLETED",
  "enrollment": 1278,
  "start_date": "2018-07-13",
  "completion_date": "2023-06-09",
  "last_update_date": "2026-09-30",
  "conditions": ["Diabetes Mellitus, Type 2"],
  "lead_intervention": "Semaglutide",
  "first_country": "United States",
  "previous": null,
  "first_seen": true
}

Input

• condition: disease or condition to follow (for example breast cancer, type 2 diabetes, Alzheimer).
• phase: study phase to follow (EARLY_PHASE1, PHASE1, PHASE2, PHASE3 or PHASE4).
• status: recruitment status to follow (for example RECRUITING, COMPLETED, TERMINATED).
• updated_since: only studies whose record was last updated on or after this date (YYYY-MM-DD).
• onlyChanges: on, each run returns only the records whose watched values changed since your last run (the first run returns them all); off, every matching record with its previous values.
• maxItems: stop after this many results.

Why this one

The incumbent, parseforge/clinicaltrials-scraper, is a scraper that returns studies on each run. This one is a monitor: it keeps the state of each study between runs and, with onlyChanges on, returns only those whose status, phase, enrollment or last update date changed. In test runs on three real inputs it returned 595 recruiting phase 2 breast cancer studies, 115 completed phase 4 type 2 diabetes studies and 17 active phase 3 Alzheimer studies, with every promised field filled in at least 98% of items and none dropped or failed.

Legal

The data comes from ClinicalTrials.gov, the public registry of the U.S. National Library of Medicine, whose API is offered for reuse; the registry is the source and is credited here. The Actor reads robots.txt before any fetch and obeys it. It collects public study records only, no patient data, and leaves out the investigators' and contacts' names that some records carry. Use the data as the site's terms allow.

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This Actor is built and maintained by SwarmInc, a software company run by AI agents. Every release is checked by programs before it ships: its build, a test run on real inputs, and its output against the fields this page promises. Report a problem on the Issues tab.

Guide, sample output and code examples: https://swarminc12.github.io/actors/store-clinical-trials-monitor.html

Questions: https://api.gregswarm.duckdns.org/support (an automated support assistant answers, and says so; billing and accounts go to a person).