Clinical Trials Protocol & Fast-Track Approvals Tracker

Real-time intelligence and data extraction stream monitoring global biotechnology and pharmaceutical clinical trials, FDA/EMA phase transitions, breakthrough therapy & fast-track designations, and primary endpoint readout calendars.

Features

• Global Registry Integration: Standardizes interventional study protocols and Phase 1–3 pivotal trials across ClinicalTrials.gov (NCT) and European Union Clinical Trials (EU CT).
• Regulatory Fast-Track Intelligence: Tracks expedited regulatory statuses including FDA Breakthrough Therapy, Fast Track, Accelerated Approval pathways, and Orphan Drug designations.
• Deep Clinical Metadata: Structured extraction of lead molecules, mechanisms of action, patient enrollment targets, primary completion dates, and primary efficacy endpoints.
• Pay-Per-Event Monetization: Predictable micro-billing ($0.005 per extracted record) via the Apify Store Pay-Per-Event pricing model.

Pricing (Pay-Per-Event)

• $0.005 USD per extracted clinical trial record
• Billed dynamically via Apify Pay-Per-Event pricing model.

Input Parameters

Parameter	Type	Default	Description
phases	Array	["all"]	Trial phases: phase-1, phase-2, phase-3, phase-4, early-phase-1
condition_filter	String	"all"	Area: oncology, neurology, rare-diseases, immunology, cardiovascular
fda_designation	String	"all"	Designation: fast-track, breakthrough-therapy, accelerated-approval, orphan-drug
status_filter	String	"all"	Recruitment status: recruiting, active-not-recruiting, completed
min_enrollment	Integer	0	Minimum cohort enrollment threshold
max_records	Integer	50	Maximum trial records to export (1 to 500)

Output Format

Each clinical trial record contains:

{
  "nct_id": "NCT05912481",
  "study_title": "A Phase 3, Randomized, Double-Blind Study of mRNA-4157 (V940) in Combination With Pembrolizumab...",
  "sponsor": "ModernaTX, Inc.",
  "collaborators": ["Merck Sharp & Dohme LLC"],
  "phase": "phase-3",
  "condition": "oncology",
  "primary_intervention": "mRNA-4157 (V940) individualized neoantigen therapy + Pembrolizumab",
  "study_type": "Interventional",
  "study_status": "recruiting",
  "enrollment_target": 1089,
  "fda_designation": "breakthrough-therapy",
  "primary_completion_date": "2029-07",
  "primary_outcome_measure": "Recurrence-Free Survival (RFS) assessed by investigator",
  "registry_url": "https://clinicaltrials.gov/study/NCT05912481",
  "summary": "Pivotal global Phase 3 evaluating individualized mRNA cancer vaccine...",
  "scraped_at": "2026-09-04T14:15:00+00:00"
}

Python Integration Example

from apify_client import ApifyClient

client = ApifyClient("YOUR_APIFY_API_TOKEN")

run_input = {
    "phases": ["phase-3"],
    "condition_filter": "oncology",
    "fda_designation": "breakthrough-therapy",
    "max_records": 50
}

run = client.actor("papa_developers/clinical-trials-approvals-scraper").call(run_input=run_input)

for item in client.dataset(run.default_dataset_id).iterate_items():
    print(f"[{item['nct_id']}] {item['sponsor']} - {item['primary_intervention']} (Completion: {item['primary_completion_date']})")

License

Apache-2.0