You can access the ClinicalTrials.gov Update Watcher programmatically from your own applications by using the Apify API. You can also choose the language preference from below. To use the Apify API, you’ll need an Apify account and your API token, found in API & Integrations in Apify Console.

Python

JavaScript

CLI

OpenAPI

HTTP

MCP

$echo '{
<  "mode": "watchlist",
<  "sourceMode": "startUrls",
<  "startUrls": [
<    {
<      "url": "https://clinicaltrials.gov/api/v2/studies",
<      "sourceId": "CLINICALTRIALS-GOV-API",
<      "userData": {
<        "sourceId": "CLINICALTRIALS-GOV-API"
<      }
<    },
<    {
<      "url": "https://clinicaltrials.gov/",
<      "sourceId": "CLINICALTRIALS-GOV",
<      "userData": {
<        "sourceId": "CLINICALTRIALS-GOV"
<      }
<    }
<  ],
<  "maxItems": 10,
<  "lookbackDays": 30,
<  "includeRaw": false,
<  "outputMode": "buyer-ready-records",
<  "overallTimeoutSecs": 120,
<  "requestTimeoutSecs": 20
<}' |
<apify call zentrafoundry/clinicaltrials-protocol-amendment-watcher --silent --output-dataset

ClinicalTrials.gov last-update watcher API through CLI

The Apify CLI is the official tool that allows you to use ClinicalTrials.gov Update Watcher locally, providing convenience functions and automatic retries on errors.

Install Apify CLI

Using installation script (macOS/Linux):

$curl -fsSL https://apify.com/install-cli.sh | bash

Using installation script (Windows):

$irm https://apify.com/install-cli.ps1 | iex

Using Homebrew:

$brew install apify-cli

Using npm:

$npm install -g apify-cli

Other API clients include:

ClinicalTrials.gov Update Watcher API in Python

ClinicalTrials.gov Update Watcher API in JavaScript

ClinicalTrials.gov Update Watcher OpenAPI definition

ClinicalTrials.gov Update Watcher API

llms.txt Snapshot (Cursor)

zentrafoundry/llms-ai-crawler-visibility-auditor

Public cursor.com/llms.txt headings and links. Not a crawler-readiness score. $0.043 / line.

Zentra

ClinicalTrials.gov Scraper

thriftykiwi/clinical-trials-scraper

Search ClinicalTrials.gov v2 studies by keyword: NCT ID, title, status, phase, conditions, sponsor, enrollment, locations and dates. Free API, no key required.

Thrifty Kiwi

ClinicalTrials.gov Scraper - Studies & Sponsors

antishock/clinicaltrials-gov-studies-scraper

Extract clinical trials from ClinicalTrials.gov: condition, intervention, phase, sponsor, enrollment, eligibility, sites and timelines. Filter by condition, drug, sponsor, country and recruitment status. Official NIH API, no key required.

Ryan Zinburg

Computrabajo Jobs Scraper — Ofertas MX/CO

noahadler/computrabajo-jobs

Scrape Computrabajo ofertas (México, Colombia and other LATAM sites): title, company, city and offer URL. Salary only when Computrabajo publishes it on the card. HTTP + RESIDENTIAL country of the query (MX default).

Noah Adler

FlowMint JSON Repair

yummy_cormorant/flowmint

Repair malformed JSON into valid JSON. Returns the repaired JSON text, parsed value, and a changed flag. Designed for reliable automated workflows with no LLM, proxy, or external API keys required.

Taras

GDACS Alerts Scraper - Disaster, Earthquake, Flood, Wildfire

snow_leo_data/disaster-alerts-scraper

776 disaster events where one GDACS query returns 100, and 704 earthquakes in 21 queries against 100. 56 fields per event. Global disaster alerts with wildfire data, tropical cyclone, drought and flood data, red and orange alert levels. UN and European Commission source.

Snow Leo Data

RSS Feed Reader: RSS & Atom to JSON, Bulk, $1/1K

conserving_celerytop/rss-feed-reader

Read any list of RSS and Atom feeds and get one row per item: title, link, publication date, summary, categories, image and enclosure, optionally the full content. Filter by date. $1 per 1,000 items; broken feeds are free.

Don Mangu

FDA AccessGUDID DI Commercial Distribution Status Monitor

plym-actor-factory/us-fda-accessgudid-di-status-monitor

Watch Primary Device Identifiers and emit typed DISTRIBUTION_STATUS_CHANGED / RECORD_STATUS_CHANGED / APPEARED / DROPPED events from NLM AccessGUDID. Not PPEF twin; not HC DPD twin; not 510(k) clearance twin; not openFDA recall twin.

Daniel Witney

🧬 ClinicalTrials Status History & Termination Intelligence

snuggly_beanie_970/clinicaltrials-status-history-intelligence

Recover verified ClinicalTrials.gov status transitions by NCT ID. Export previous/new status, transition date, termination signals, changed modules and sponsor context.

Ilia

No-Spec Vendor JSON API Response Drift Watcher

kingii98/no-spec-vendor-json-api-response-drift-watcher

Watch public JSON GET endpoints for response-shape drift without an OpenAPI spec. The Actor learns the shape from the response, compares it against a stored baseline, and reports each field-level change with a breaking flag.