You can access the ClinicalTrials.gov Update Watcher programmatically from your own applications by using the Apify API. You can also choose the language preference from below. To use the Apify API, you’ll need an Apify account and your API token, found in API & Integrations in Apify Console.

Python

JavaScript

CLI

OpenAPI

HTTP

MCP

1from apify_client import ApifyClient
2
3# Initialize the ApifyClient with your Apify API token
4# Replace '<YOUR_API_TOKEN>' with your token.
5client = ApifyClient("<YOUR_API_TOKEN>")
6
7# Prepare the Actor input
8run_input = {
9    "mode": "watchlist",
10    "sourceMode": "startUrls",
11    "startUrls": [
12        {
13            "url": "https://clinicaltrials.gov/api/v2/studies",
14            "sourceId": "CLINICALTRIALS-GOV-API",
15            "userData": { "sourceId": "CLINICALTRIALS-GOV-API" },
16        },
17        {
18            "url": "https://clinicaltrials.gov/",
19            "sourceId": "CLINICALTRIALS-GOV",
20            "userData": { "sourceId": "CLINICALTRIALS-GOV" },
21        },
22    ],
23    "maxItems": 10,
24    "lookbackDays": 30,
25    "includeRaw": False,
26    "outputMode": "buyer-ready-records",
27    "overallTimeoutSecs": 120,
28    "requestTimeoutSecs": 20,
29}
30
31# Run the Actor and wait for it to finish
32run = client.actor("zentrafoundry/clinicaltrials-protocol-amendment-watcher").call(run_input=run_input)
33
34# Fetch and print Actor results from the run's dataset (if there are any)
35print(f"💾 Check your data here: https://console.apify.com/storage/datasets/{run.default_dataset_id}")
36for item in client.dataset(run.default_dataset_id).iterate_items():
37    print(item)
38
39# 📚 Want to learn more 📖? Go to → https://docs.apify.com/api/client/python/docs/quick-start

ClinicalTrials.gov last-update watcher API in Python

The Apify API client for Python is the official library that allows you to use ClinicalTrials.gov Update Watcher API in Python, providing convenience functions and automatic retries on errors.

Install the apify-client

$pip install apify-client

Other API clients include:

ClinicalTrials.gov Update Watcher API in JavaScript

ClinicalTrials.gov Update Watcher API through CLI

ClinicalTrials.gov Update Watcher OpenAPI definition

ClinicalTrials.gov Update Watcher API

llms.txt Snapshot (Cursor)

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ClinicalTrials.gov Scraper

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antishock/clinicaltrials-gov-studies-scraper

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noahadler/computrabajo-jobs

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yummy_cormorant/flowmint

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snow_leo_data/disaster-alerts-scraper

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RSS Feed Reader: RSS & Atom to JSON, Bulk, $1/1K

conserving_celerytop/rss-feed-reader

Read any list of RSS and Atom feeds and get one row per item: title, link, publication date, summary, categories, image and enclosure, optionally the full content. Filter by date. $1 per 1,000 items; broken feeds are free.

Don Mangu

FDA AccessGUDID DI Commercial Distribution Status Monitor

plym-actor-factory/us-fda-accessgudid-di-status-monitor

Watch Primary Device Identifiers and emit typed DISTRIBUTION_STATUS_CHANGED / RECORD_STATUS_CHANGED / APPEARED / DROPPED events from NLM AccessGUDID. Not PPEF twin; not HC DPD twin; not 510(k) clearance twin; not openFDA recall twin.

Daniel Witney

🧬 ClinicalTrials Status History & Termination Intelligence

snuggly_beanie_970/clinicaltrials-status-history-intelligence

Recover verified ClinicalTrials.gov status transitions by NCT ID. Export previous/new status, transition date, termination signals, changed modules and sponsor context.

Ilia

No-Spec Vendor JSON API Response Drift Watcher

kingii98/no-spec-vendor-json-api-response-drift-watcher

Watch public JSON GET endpoints for response-shape drift without an OpenAPI spec. The Actor learns the shape from the response, compares it against a stored baseline, and reports each field-level change with a breaking flag.