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FDA Orange Book Patent & Exclusivity Tracker — Quarterly Diff

Purpose-built FDA Orange Book diff stream — NDA/ANDA/BLA patent listings, exclusivity grants, LoE + TE-code shifts as JSONL. FDA-vocabulary-aware vs general-purpose scrapers like Browse AI; per-record metered vs Cortellis $35-50k/yr seat tax for pharma BI + IP + generics. Public runs.

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from $3.40 / 1,000 result storeds

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ChangeWire

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FDA Orange Book Scraper

parseforge/fda-orange-book-scraper

Scrape the FDA Orange Book of approved drug products with therapeutic equivalence evaluations. Get NDA, ingredient, dosage form, strength, route, applicant, marketing status, TE code, RLD/RS flags, exclusivity and patent data. Perfect for pharma research, payers, and generics intelligence.

ParseForge

FDA Orange Book Scraper

labrat011/fda-orange-book-scraper

Extract FDA Orange Book data — drug patent expirations, exclusivity periods, generic equivalents, and therapeutic equivalence ratings. No API key required.

mick_

FDA Orange Book Patent Expirations Monitor

oobr/fda-orange-book-patent-expirations

Monthly Orange Book extracts with patent expiration dates, applicant, active ingredient — for generics timing & IP diligence.

OOBR Team

USPTO TTAB Docket Diff API — Opposition & Cancellation Tracker

changewire/uspto-ttab-docket-extractor

Purpose-built diff stream for USPTO TTAB — per-proceeding status / filings / parties / marks / deadlines / decisions as JSONL. TTABVUE-API-native vocab vs general-purpose scrapers like Browse AI; per-record metered vs CompuMark $20-200k/yr for trademark counsel + IP litigators. Public runs.

ChangeWire

Grants.gov Opportunity Alert — Daily Federal Grant Diff

changewire/grantsgov-opportunity-alert

Purpose-built federal NOFO diff stream — Grants.gov REST API with NIH/NSF/DOE/USDA program-officer + eligibility + close-date diff records as JSONL. Federal-only focus vs Instrumentls nonprofit-foundation breadth; per-record metered ($0.0034) vs Browse AIs $19-249/mo subscription tax. Public runs.

ChangeWire

EPA ECHO Compliance Diff API — CAA, CWA, RCRA, SDWA Enforcement

changewire/epa-echo-compliance

Purpose-built diff stream for EPA ECHO — facility-flip / violation-class / enforcement-case / CAA/CWA/RCRA/SDWA permit changes as JSONL. ECHO-API-native vocab vs general-purpose scrapers like Browse AI; per-record metered vs Cority $30-200k/yr seat tax for ESG, EJ, journalism, NGOs. Public runs.

ChangeWire

ClinicalTrials.gov Protocol Change Monitor

changewire/clinicaltrials-protocol-diff

Purpose-built diff stream for ClinicalTrials.gov v2 — per-NCT status / enrollment / endpoint / sponsor / eligibility / locations changes as JSONL. Replaces Evaluate Pharma + Citeline + general-purpose scrapers like Browse AI for pharma BI, drug-discovery AI agents, biotech reporters. Public runs.

ChangeWire

NOAA Storm Events Diff API — Damage Revisions for Cat Modeling

changewire/noaa-storm-events-diff

Purpose-built NOAA Storm Events post-event-audit diff — F-scale upgrades, damage revisions, casualty deltas as JSONL. Storm-vocabulary-aware vs Browse AI; per-record metered vs AccuWeather Enterprise / StormGeo / CoreLogic $25-50k/yr seat tax for actuarial + FEMA + litigation cohorts. Public runs.

ChangeWire

Drugs@FDA Approvals Scraper

parseforge/openfda-drugsfda-scraper

Export Drugs@FDA approval records from openFDA. Search 29k+ NDA, ANDA, and BLA applications by application number, sponsor, or product. Pull application details, sponsor, submissions history, products, dosage forms, routes, and marketing status.

ParseForge